Gallstone disease among policlinic staff: its development risks in different professional groups

M. A. Osadchuk; A. A. Svistunov; E. D. Mironova; N. P. Korzhenkov; M. V. Trushin

M. A. Osadchuk Federal State Autonomous Education Institution of Higher Training I.M.Sechenov First Moscow State Medical University (Sechenov University).
A. A. Svistunov Federal State Autonomous Education Institution of Higher Training I.M. Sechenov First Moscow State Medical University (Sechenov University).
E. D. Mironova Federal State Autonomous Education Institution of Higher Training I.M. Sechenov First Moscow State Medical University (Sechenov University).
N. P. Korzhenkov Federal State Autonomous Education Institution of Higher Training I.M. Sechenov First Moscow State Medical University (Sechenov University).
M. V. Trushin Kazan Federal University, Kazan, Russia

Keywords: Gallstone disease, medical staff, risk factors for gallstone disease.

Abstract

The aim. Identification of risk factors for gallstone disease (GDS) development between different professional groups of polyclinic medical staff. Material and methods. 75 medical staff members were divided into two groups (1st group: 30 doctors; 2nd group: 45 nurses). All of them were interviewed fo r information about profession, gender, age, waist circumference (WC), body mass index (BMI), smoking, arterial hypertension (AH), diabetes mellitus (DM) and hypercholesterolemia. In addition, women were interviewed about the number of pregnancies, ostmenopause and taking oral contraceptive pills (OCPs). To assess physical activity, a short international questionnaire on physical activity (IPAQ) was used. To identify the presence of professional burnout (PB) syndrome we applied the Maslach Burnout Inventory (MBI) questionnaire, adapted by N.Е. Vodopianova for medical staff. At the final stage, the data of abdominal organs ultrasound examination were analyzed based on the materials of medical staff outpatient records. Results. The GSD prevalence among doctors was 33.3%, and 24.4% among nurses. In both groups age, AH, weight, WC and BMI contribute to GSD formation. In the first group of individuals with GSD, the level of total cholesterol (TC) was significantly higher. In the same group extremely high PB, postmenopause (p <0.05) and hypodynamia (p <0.1) were much more common. In the second group, there were more DM cases and pregnancies (p <0.05). Conclusion. The medical staff of the clinic has a high GSD incidence, whose frequency depends not only on classical risk factors prevalence, but is also determined by profession peculiarities, characterized by high psychological stress and lower physical activity of physicians, compared to nurses.

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Author Biographies

M. A. Osadchuk, Federal State Autonomous Education Institution of Higher Training I.M.Sechenov First Moscow State Medical University (Sechenov University).

Federal State Autonomous Education Institution of Higher Training I.M.Sechenov First Moscow State Medical University (Sechenov University).

A. A. Svistunov, Federal State Autonomous Education Institution of Higher Training I.M. Sechenov First Moscow State Medical University (Sechenov University).

Federal State Autonomous Education Institution of Higher Training I.M. Sechenov First Moscow State Medical University (Sechenov University).

E. D. Mironova, Federal State Autonomous Education Institution of Higher Training I.M. Sechenov First Moscow State Medical University (Sechenov University).

Federal State Autonomous Education Institution of Higher Training I.M. Sechenov First Moscow State Medical University (Sechenov University)..

N. P. Korzhenkov, Federal State Autonomous Education Institution of Higher Training I.M. Sechenov First Moscow State Medical University (Sechenov University).

Federal State Autonomous Education Institution of Higher Training I.M. Sechenov First Moscow State Medical University (Sechenov University).

M. V. Trushin, Kazan Federal University, Kazan, Russia

Kazan Federal University, Kazan, Russia

References

Аchkasov E.E., Mel'nikov А.I., Belozerov B.G., YAroslavskaya M.А., Osadchuk M.А., Аsanov А.YU., Kuznetsov N.А. (2019) Psychological rehabilitation of medical workers with emotional burnout syndrome. Meditsina truda i promyshlennaya ehkologiya; (1):15-19. doi:https://doi.org/10.31089/1026-9428-2019-1-15-19.

de Bari O, Wang HH, Portincasa P, Liu M, Wang DQ-H. (2015) The deletion of the estrogen receptor α gene reduces susceptibility to estrogen-induced cholesterol cholelithiasis in female mice. Biochim Biophys Acta;1852(10 0 0):2161-2169. doi:10.1016/j.bbadis.2015.07.020.

Ermolina T.A., Martynova N.A., Kalinin A.G. (2017). The incidence of health workers (professional aspects). Zdorov’e i obrazovanie v XXI veke;19(5):85-88.

Hidalgo KD, Mielke GI, Parra DC. (2016). Health promoting practices and personal lifestyle behaviors of Brazilian health professionals. BMC Public Health. 16. doi:10.1186/s12889-016-3778-2.

Hou L, Shu X-O, Gao Y-T. (2009). Anthropometric measurements, physical activity, and the risk of symptomatic gallstone disease in Chinese women. Ann Epidemiol;19(5):344-350. doi:10.1016/j.annepidem.2008.12.002.

Hung S-C, Liao K-F, Lai S-W, Li C-I, Chen W-C (2011). Risk factors associated with symptomatic cholelithiasis in Taiwan: a population-based study. BMC Gastroenterol. 11:111. doi:10.1186/1471-230X-11-111.

Kobyakova O.S., Deev I.A., Kulikov E.S., Homyakov K.V., Pimenov I.D., Zagromova T.A., Balaganskaya M.A. (2017). Burnout of physicians in the Russian Federation modeled by the Tomsk region. Social’nye aspekty zdorov’ya naseleniya.55(3).

Kono S, Eguchi H, Honjo S. (2002). Cigarette Smoking, Alcohol Use, and Gallstone Risk in Japanese Men. DIG. 65(3):177-183. doi:10.1159/000064938.

Kosarev V.V., Dvojnikov S.I., Dudinceva N.V. (2013). Health status and quality of life of occupational health workers. Ohrana truda i tehnika bezopasnosti v uchrezhdeniyah zdravoohraneniya;(2):12-15.

Lammert F, Gurusamy K, Ko CW. Gallstones (2016). Nat Rev Dis Primers. ;2:16024. doi:10.1038/nrdp.2016.24.

Lee M-C, Yang Y-C, Chen Y-C, Huang S-C (2014). Sa2047 Estrogen Causes Relaxation of Human Gallbladder via G Protein-Coupled Estrogen Receptors. Gastroenterology;146(5):S-363. doi:10.1016/S0016-5085(14)61314-7.

National Research Center for Preventive Medicine of the Russian Federation. (2019) Clinical treatment protocol multicenter simultaneous observational study "Assessment of the level of physical activity in patients with overweight and obese in the Russian Federation". 2017; 13-14 Accessed July 14, 2019. https://scardio.ru/content/activities/2017/protokol_fiz_akt_ozhir.pdf

Osadchuk MA, Mironova ED, Vasileva, IN, Korzhenkov N.P., Achkasov E.E., Gulyaev P.V., Osadchuk M.M., Trushin M.V. (2019a) Oral medical dissolution of gallstones in patients with gallstone disease. Pren Méd Argent;105(1):34-40.

Osadchuk M.A., Kireeva N.V., Vasil'eva I.N., Mironova E.D. (2019b). The influence of the severity of metabolic disorders on the diameter of the stones in the gallbladder: clinical and instrumental and laboratory data. Terapiya;3(29):55-59. doi: https: //dx.doi.org/10.18565/

Osadchuk M.A., Mironova E.D., Balashov D.V., Osadchuk M.M. (2019c) Course of gallstone disease in persons with metabolic discorders. CONSILIUM MEDICUM; 21(8):74-77. doi.org/10.26442/20751753.2019.8.190548.

Pak M, Lindseth G. (2016). Risk Factors for Cholelithiasis. Gastroenterol Nurs;39(4):297-309. doi:10.1097/SGA.0000000000000235.

Portincasa P, Moschetta A, Palasciano G. (2006). Cholesterol gallstone disease. Lancet;368(9531):230-239. doi:10.1016/S0140-6736(06)69044-2.

Rodriguez S, Gaunt TR, Guo Y. (2016) Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array. Eur J Hum Genet. 24(1):106-112. doi:10.1038/ejhg.2015.63.

Ryu S, Chang Y, Kim YS, Kim HJ. (2018) Prolonged sitting increases the risk of gallstone disease regardless of physical activity: a cohort study. Scandinavian Journal of Gastroenterology;53(7):864-869. doi:10.1080/00365521.2018.1476910.

Sekiya N, Kuroda Y, Nakajima K. (2017). Views on life and death of physicians, nurses, cancer patients and general population in Japan. PLoS ONE;12(5):e0176648. doi:10.1371/journal.pone.0176648.

Shabanzadeh DM, Novovic S. (2017) Alcohol, smoking and benign hepato-biliary disease. Best Pract Res Clin Gastroenterol;31(5):519-527. doi:10.1016/j.bpg.2017.09.005.

Stinton LM, Shaffer EA. (2012). Epidemiology of gallbladder disease: cholelithiasis and cancer. Gut Liver;6(2):172-187. doi:10.5009/gnl.2012.6.2.172.

Trifonova E.V., Ryzhikova O.V., Sajfutdinov R.G. (2011). Prevalence of cholelithiasis among oil companies of JSC ”TATNEFT”. Prakticheskaya medicina;(50):9-13.

Vakhrushev YM, Khokhlacheva NA, Sergeeva NN. (2017). Psychoemotional and autonomic states in patients with cholelithiasis. Ter Arkh; 89(4):64-68. doi:10.17116/terarkh201789464-68.

Vodop’yanova N.E. (2009). Psihodiagnostika stressa. - SPb.: Piter; 152-153.

Wang S, Wang Y, Xu J, Chen Y. (2017). Is the oral contraceptive or hormone replacement therapy a risk factor for cholelithiasis: A systematic review and meta-analysis. Medicine (Baltimore). ;96(14):e6556. doi:10.1097/MD.0000000000006556.

Zhu T, Zhang SS, Chen DY. (2016). Job burnout and related influencing factors in community medical staff in Nanchong, China. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2016;34(12):928-930. doi:10.3760/cma.j.issn.1001-9391.2016.12.011.