Vol. 14 No. 86 (2025): Continuous Edition (February – December 2025)
Articles

Plants discovered in Costa Rica between 2010 and 2020 and their possible pharmacological use

Rolando Vargas-Zuñiga
University of Costa Rica, San Pedro, Costa Rica
Author Biography

Master's Degree in Intellectual Property, Researcher at the Pharmaceutical Research Institute (INIFAR), Faculty of Pharmacy, University of Costa Rica, San Pedro, Costa Rica

Jeimy Blanco-Barrantes
University of Costa Rica, San Pedro, Costa Rica
Author Biography

MSc in Drug Analysis and Quality Control, Researcher at the Pharmaceutical Research Institute (INIFAR), Faculty of Pharmacy, University of Costa Rica, San Pedro, Costa Rica

Jeniffer Sandí Flores
University of Costa Rica, San Pedro, Costa Rica
Author Biography

Graduate in Pharmacy, Researcher at the Institute of Pharmaceutical Research (INIFAR), Faculty of Pharmacy, University of Costa Rica, San Pedro, Costa Rica

German Madrigal-Redondo
University of Costa Rica, San Pedro, Costa Rica
Author Biography

MSc in Drug Analysis and Quality Control, Researcher at the Pharmaceutical Research Institute (INIFAR), Faculty of Pharmacy, University of Costa Rica, San Pedro, Costa Rica

Published 2025-02-28

Keywords

  • Costa Rica,
  • endemic,
  • ethnobotanical,
  • medicinal uses,
  • new species

How to Cite

Vargas-Zuñiga, R., Blanco-Barrantes, J., Sandí Flores, J., & Madrigal-Redondo, G. (2025). Plants discovered in Costa Rica between 2010 and 2020 and their possible pharmacological use. Amazonia Investiga, 14(86), 51–64. https://doi.org/10.34069/AI/2025.86.02.5

Abstract

Costa Rica is known for having 6% of the world's biodiversity, approximately 12% of the plant species that exist in the country are endemic and because in Costa Rica the use of plants for medicinal purposes has been a tradition, it is important to know the potential pharmacological activities of the species that have recently been discovered. A bibliographic search was carried out under the criteria: Costa Rican species, endemic, recently discovered (2010-2020), that have few studies, that present ethnobotanical uses or that the family to which they belong, report this type of medicinal use. One or more criteria had to be met and, therefore, information on plants from 18 families is reported. Finally, it is very important to carry out more research on the large number of plant species that have been discovered in Costa Rica since it could be useful to know the molecular and phytochemical profile of these species both to know if they have pharmacological potential, as well as to know better its taxonomic and evolutionary classification.

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References

  1. Acebey Dávalos, A., Thorsten, K., & Vázquez Torres, M. (2012). ¿Qué es una especie endémica? Gaceta, 121. https://www.researchgate.net/publication/291693973_Que_es_una_especie_endemica
  2. Aguilar Fernández, R., Poveda Álvarez, L. J., & Santamaría-Aguilar, D. (2018). Hymenaea osanigraseminae: Un nuevo guapinol (Fabaceae) del Pacífico central y sur de Costa Rica. Phytoneuron, 20, 1–12. https://www.phytoneuron.net/2018Phytoneuron/20PhytoN-Hymenaea.pdf
  3. Aguilar Sandí, D. (2018). Diversidad de plantas en Costa Rica: Determinación y publicación de una nueva especie. Blog RBT. https://revistas.ucr.ac.cr/index.php/rbt/article/view/35753/36475
  4. Al-Amin, M., Rahiman, S. S. F., Hossain, C. F., Khairuddean, M., & Salhimi, S. M. (2023). Natural products from Rhynchostylis retusa (Orchidaceae), their chemophenetic significance and bioactivity. Biochemical Systematics and Ecology, 111, 104737. https://doi.org/10.1016/J.BSE.2023.104737
  5. Alzate Tamayo, L. M., Arteaga González, D. M., & Jaramillo Garcés, Y. (2008). Propiedades farmacológicas del Algarrobo (Hymenaea courbaril Linneaus) de interés para la industria de alimentos. Revista Lasallista de Investigación, 5(2), 100–111. http://www.redalyc.org/articulo.oa?id=69550213
  6. Antonelo, F. A., Rodrigues, M. S., Cruz, L. C., Pagnoncelli, M. G., Alves da Cunha, M. A., Bonatto, S. J. R., Busso, C., Wagner Júnior, A., & Montanher, P. F. (2023). Bioactive compounds derived from Brazilian Myrtaceae species: Chemical composition and antioxidant, antimicrobial and cytotoxic activities. Biocatalysis and Agricultural Biotechnology, 48. https://doi.org/10.1016/J.BCAB.2023.102629
  7. Berto, A., Ribeiro, A. B., de Souza, N. E., Fernandes, E., & Chisté, R. C. (2015). Bioactive compounds and scavenging capacity of pulp, peel and seed extracts of the Amazonian fruit Quararibea cordata against ROS and RNS. Food Research International, 77, 236–243. https://doi.org/10.1016/J.FOODRES.2015.06.018
  8. Cedeño-Fonseca, M., Karremans, A. P., & Ortiz, O. O. (2018). Monstera limitaris (Araceae), a new species from the border between Costa Rica and Panama. Phytotaxa, 376(1), 37–42. https://doi.org/10.11646/PHYTOTAXA.376.1.4
  9. Contreras Arias, A., & Campregher, C. (2010). Plantas medicinales en una plantación de cacao en Guápiles, Costa Rica. UNED Research Journal, 2(2), 231–237. https://doi.org/https://doi.org/10.22458/urj.v2i2.159
  10. Debouck, D. G., Araya-Villalobos, R., & Chaves-Barrantes, N. (2018). Phaseolus angucianae (Leguminosae: Phaseoleae), a new bean species from Fila cruces of southeastern Costa Rica. Journal of the Botanical Research Institute of Texas, 12(2), 507–520. https://doi.org/10.17348/jbrit.v12.i2.953
  11. Debouck, D. G., Chaves-Barrantes, N., & Araya-Villalobos, R. (2020). Phaseolus albicarminus (Leguminosae, Phaseoleae), a new wild bean species from the subhumid forests of southern central Costa Rica. Phytotaxa, 449(1), 1–14. https://doi.org/10.11646/PHYTOTAXA.449.1.1
  12. Dressler, R. L., & Pupulin, F. (2014). Two new white-flowered species of Sobralia (Orchidaceae) from Costa Rica. Harvard Papers in Botany, 19(1), 117–122. https://doi.org/10.3100/hpib.v19iss1.2014.n8
  13. Estrada, A., Rivera, G., & Solano, J. (2016). Passiflora Chimuensis, una nueva especie y primer registro de la sección Pseudoastrophe (Subgénero Astrophea, Passifloraceae) en Mesoamérica. Journal of the Botanical Research Institute of Texas, 10(1), 71–76. https://acortar.link/S1kut0
  14. Estrada-Chavarría, A., & Rivera, G. (2014). Passiflora Soliana, una especie nueva de Passiflora (Passifloraceae) del Pacífico Sur de Costa Rica. Journal of the Botanical Research Institute of Texas, 8(1), 19–24. https://www.biodiversitylibrary.org/part/280451
  15. Farràs, A., Mitjans, M., Maggi, F., Caprioli, G., Vinardell, M. P., & López, V. (2021). Polypodium vulgare L. (Polypodiaceae) as a source of bioactive compounds: polyphenolic profile, cytotoxicity and cytoprotective properties in different cell lines. Frontiers in Pharmacology, 12(727528). https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.727528/full
  16. Fernández, M., & Bogarín, D. (2013). A new species of Trichosalpinx (Orchidaceae: Pleurothallidinae) from Costa Rica. Brittonia, 65(1), 96–101. https://doi.org/10.1007/S12228-012-9265-X
  17. Fernández, M., Bogarín, D., Karremans, A. P., & Jiménez, D. (2014). New species and records of Orchidaceae from Costa Rica. Lankesteriana International Journal on Orchidology, 13(3), 259-282.
  18. García-González, M., & Morales, C. O. (2005). Análisis de la literatura sobre plantas medicinales en Costa Rica (1930-2001). Lankesteriana: International Journal on Orchidology, 5(1), 3–40. https://doi.org/10.15517/LANK.V5I1.19817
  19. Germosén-Robineau, L. (2014). Farmacopea Vegetal Caribeña (3rd ed.). TRAMIL. https://fitoterapiabrasil.com.br/sites/default/files/documentos-oficiais/tram-far3.pdf
  20. Gonçalves dos Santos, J., Fernandes, C. C., & Dantas Miranda, M. L. (2024). Ferns with important ethnomedicinal value and chemical and biological aspects of Nephrolepis cordifolia: brief review. Acta Scientiarum. Biological Sciences, 46, 2–7. Doi: 10.4025/actascibiolsci.v46i1.69341
  21. González, J. (2013). Plantas útiles de La Selva. In Flora Digital de La Selva (Ed.), Organización Para Estudios Tropicales Flora Digital de La Selva. https://sura.ots.ac.cr/florula4/docs/plantas_utiles_LS_etnobotanica_2013.pdf
  22. Guillén Rodríguez, Y., & Vargas Rojas, G. (2014). Voyria crucitasensis (Gentianaceae), una nueva especie de planta micoheterotrófica para Costa Rica. Phytoneuron, 2014–99, 1–6.
  23. Hammel, B. E. (2015). Three new species of Pentagonia (Rubiaceae) from southern central America, one foreseen, two surprising. Phytoneuron, 2015–46, 1–13. https://www.phytoneuron.net/2015Phytoneuron/46PhytoN-Pentagonia.pdf
  24. Karremans, A. P., & Bogarín, D. (2013). Three new species of Dracontia (Pleurothallidinae, Orchidaceae) from Costa Rica. Systematic Botany, 38(2), 307–315. https://doi.org/10.1600/036364413X666796
  25. Karremans, A. P., & Díaz-Morales, M. (2017). Novelties in Costa Rican Stelis (Orchidaceae: Pleurothallidinae): two new species and a new record in the “Dracontia group.” Lankesteriana: International Journal on Orchidology, 17(2), 193–202. https://doi.org/10.15517/LANK.V17I2.29928
  26. Karremans, A. P., & Lehmann Calderón, P. (2018). A highly threatened new species of Vanilla from Costa Rica. Orchids (West Palm Beach), 87(4), 304-307. https://christianafigueres.com/publications/Karremans_Lehmann_2018.pdf
  27. Karremans, A. P., & Smith, C. M. (2012). A Note on Genus Dracontia (Orchidaceae: Pleurothallidinae), with a New Species, 17(1), 13–17. https://doi.org/10.3100/025.017.0104
  28. Kriebel, R., & Almeda, F. (2012). Five new species of Miconia (Melastomataceae: Miconieae) from Costa Rica and Panama. Harvard Papers in Botany, 17(1), 53–64. https://doi.org/10.3100/025.017.0112
  29. Martins, D., & Nunez, C. V. (2015). Secondary metabolites from Rubiaceae species. Molecules, 20(7), 13422–13495. https://doi.org/10.3390/MOLECULES200713422
  30. Minchán-Herrera, P., Saldaña-Bobadilla, V., Perez-Chauca, E., & Ramirez, J. K. (2020). Argyrochosma nivea (Poir.) Windham (pteridaceae E.D.M. kirchn.), “Cuti cuti”: una revisión etnobotánica, etnofarmacológica y fitoquímica. Ethnobotany Research and Applications, 19. https://doi.org/10.32859/era.19.30.1-10
  31. Ministerio de Ambiente y Energía (MINAE). (2018). Capitulo II: El estado del ambiente costarricense. In Informe de estado del ambiente: Costa Rica 2017. https://acortar.link/QEWX7J
  32. Ministerio de Ambiente y Energía (MINAE), Sistema Nacional de Áreas de Conservación (SINAC), Comisión Nacional para la Gestión de la Biodiversidad (CONAGEBIO), & Fondo Nacional de Financiamiento Forestal (FONAFIFO). (2018). Resumen del Sexto Informe Nacional de Costa Rica ante el Convenio de Diversidad Biológica. Programa de Naciones Unidas para el Desarrollo - Apoyo técnico para que las Partes Elegibles desarrollen el Sexto Informe Nacional para el CDB (6NR-LAC) Costa Rica. https://www.cbd.int/doc/nr/nr-06/cr-nr-06-p2-es.pdf
  33. Mourão De Moura, V., De Sousa, L. A. F., Bezerra De Oliveira, R., Moura Da Silva, A. M., Chalkidis, H. de M., Nascimento Da Silva, M., Pacheco, S., & Veras Mourão, R. H. (2013). Inhibition of the principal enzymatic and biological effects of the crude venom of Bothrops atrox by plant extracts. Journal of Medicinal Plants Research, 7(31), 2330–2337. https://doi.org/10.5897/JMPR2013.5148
  34. Museo de Cultura Popular. (2024). Medicina tradicional. https://acortar.link/W3rPFw
  35. Núñez Melendez, E. (1975). Plantas medicinales de Costa Rica y su folclore. Editorial Universidad de Costa Rica.
  36. Oliveira Sabbag Cunha, G., Coelho da Cruz, D., & Severo Menezes, A. C. (2019). An overview of Miconia genus: chemical constituents and biological activities. Pharmacognosy Reviews, 13(26), 77–88. https://doi.org/10.5530/phrev.2019.2.8
  37. Parrado, C., Juarranz, A., Gilaberte, Y., Philips, N., & Gonzalez, S. (2014). Fern extract, oxidative stress, and skin cancer. In Cancer: Oxidative Stress and Dietary Antioxidants (pp. 255–264). Elsevier Inc. https://doi.org/10.1016/B978-0-12-405205-5.00025-8
  38. Qi, J., Zhou, D., Jiang, W., Chen, G., Li, W., & Li, N. (2021). Dihydrophenanthrenes from medicinal plants of Orchidaceae: A review. Chinese Herbal Medicines, 13(4), 480–493. https://doi.org/10.1016/J.CHMED.2021.10.004
  39. Roberts, M.J. (2000). Edible & Medicinal Flowers. New Africa Books. https://books.google.com/books/about/Edible_Medicinal_Flowers.html?hl=es&id=6jRsF1nOmqgC
  40. Rodríguez Navas, H. (2000). La utilidad de las plantas medicinales en Costa Rica. EUNA. https://acortar.link/mw3Sfy
  41. Rojas Alvarado, A. F. (2017a). A new species and three hybrids in the ferns from Cocos Island, Puntarenas, Costa Rica. Acta Botanica Malacitana, 42(1), 91–99. https://doi.org/10.24310/abm.v42i1.2383
  42. Rojas Alvarado, A. F. (2017b). Novedades en Pteris L. (Pteridaceae) para Costa Rica. Acta Botanica Malacitana, 42(1), 165–170. https://doi.org/10.24310/abm.v42i1.2384
  43. Rojas Alvarado, A. F. (2017c). Tres especies nuevas de Hymenophyllum Sm. (Hymenophyllaceae; Pteridophyta) para Costa Rica y Colombia. Acta Botanica Malacitana, 42(1), 171–176. https://doi.org/10.24310/abm.v42i1.3009
  44. Rojas Alvarado, A. F., & Baaijen-Harteveld, W. (2017). Three new species of Elaphoglossum Scott ex J. Sm. (Dryopteridaceae) from the Pacific of Costa Rica. Acta Botanica Malacitana, 42(1), 125–129. https://doi.org/10.24310/abm.v42i1.2382
  45. Rojas Alvarado, A. F., & Muñoz Cambronero, P. E. (2017). A new species of Elaphoglossum Schott ex J. Sm. (Dryopteridaceae) from Costa Rica. Acta Botanica Malacitana, 42(1), 49–52. https://doi.org/10.24310/abm.v42i1.2973
  46. Rojas-Alvarado, A. F.R. (2011). New species and new records of ferns (Pteridophyta: Polypodiales) from Cocos Island, Costa Rica. Brenesia, 75, 7-15. https://www.researchgate.net/publication/259713307
  47. Rojas-Alvarado, A. F. (2013). Novelties in Grammitis Sw. and Stenogrammitis labiak (Polypodiaceae) from Costa Rica, Colombia, and Venezuela. Actualidades Biológicas, 35(98), 5–10. https://doi.org/10.17533/UDEA.ACBI.329199
  48. Rojas-Alvarado, A. F., & Chaves-Fallas, J. M. (2011). Una especie nueva de Spathiphyllum (Araceae) para Costa Rica. Brenesia, 75–76, 4–6. https://www.researchgate.net/publication/259712981
  49. Rostro del Muro, K. L., Morales-García, E. D., Castro-Castro, A., & Munguía-Lino, G. (2024). Riqueza, distribución y claves de identificación de la familia Gentianaceae en Nueva Galicia, México. Botanical Sciences, 102(2), 616–634. https://doi.org/10.17129/BOTSCI.3431
  50. Sánchez-González, J., & Rodríguez, A. (2017). Una especie nueva de Tachia (Gentianaceae) de la Isla del Coco, Costa Rica. Journal of the Botanical Research Institute of Texas, 11(2), 327–333. https://journals.brit.org/jbrit/article/view/1072/1009
  51. Santamaría-Aguilar, D., Estrada-Chavarría, A., & Aguilar Fernández, R. (2014). Dos nuevas especies de Myrcia (Myrtaceae), del Pacífico Sur de Costa Rica. Journal of the Botanical Research Institute of Texas, 8(2), 449–455. https://www.biodiversitylibrary.org/part/280509
  52. Seminario, J. F., Silva, W., Escalante-Zumaeta, S. B., Yuca, R., Reátegui, O., & Best, I. (2021). Biología y ecología de cuatro especies medicinales de Gentianella recolectadas para el mercado en la Región Cajamarca, Perú. Bonplandia, 30(2), 145–159. https://doi.org/10.30972/BON.3024878
  53. Struwe, L., & Kinkade, M. P. (2013). Revision of Tachia (Gentianaceae: Helieae). Systematic Botany, 38(4), 1142–1159. https://doi.org/10.1600/036364413X674797
  54. Taylor, C. M., & Gereau, R. E. (2010). Rubiacearum americanarum magna hama pars XXIV: New species of central and South American Bouvardia, Hillia, Joosia, Ladenbergia, Pentagonia, and Posoqueria. Novon: A Journal for Botanical Nomenclature, 20(4), 470–480. https://doi.org/10.3417/2009064
  55. Testo, W. L., Watkins, J. E., Pittermann, J., & Momin, R. (2015). Pteris ×caridadiae (Pteridaceae), a new hybrid fern from Costa Rica. Brittonia, 67(2), 138–143. https://doi.org/10.1007/s12228-015-9370-8
  56. Ulloa Leitón, E. (2017). Caracterización del sector productivo de plantas medicinales. Ed. PROCOMER.
  57. Wolverton, B. C., Johnson, A., & Bounds, K. (1989). Interior landscape plants for indoor Air Pollution Abatement (No. NASA-TM-101766).
  58. World Health Organization. (2000). Situación reglamentaria de los medicamentos herbarios: una reseña mundial (Organización Mundial de la Salud, Ed.). https://iris.who.int/handle/10665/66629
  59. Zafar, S., Uddin, G., & Rashid, A. (2023). A comprehensive review on the ethnobotanical, phytochemical, and pharmacological aspects of the genus Malvastrum. Fitoterapia, 171. https://doi.org/10.1016/J.FITOTE.2023.105666
  60. Zamora, N. A., Cascante Marín, A., Choi, S., & Kim, S. Y. (2017). A new species of Quararibea (Malvaceae) from Costa Rica. Phytoneuron, 2017–67, 1–6. https://www.phytoneuron.net/2017Phytoneuron/67PhytoN-Quararibea.pdf
  61. Zamora, N., Kim, S.-Y., Choi, S., & Espinoza, R. (2016). A new species of Calyptranthes (Myrtaceae) from Costa Rica. Phytoneuron, 2016–65, 1–5. https://azkurs.org/pars_docs/refs/26/25161/25161.pdf
  62. Zhou, P., Li, J.-H., Liu, Y.-Z., Zhu, Z.-W., Luo, Y., & Xiang, X.-G. (2023). Species richness disparity in tropical terrestrial herbaceous floras: Evolutionary insight from Collabieae (Orchidaceae). Molecular Phylogenetics and Evolution, 186. https://doi.org/10.1016/J.YMPEV.2023.107860